Steiner TJ, Stovner LJ, Vos T. GBD 2015: migraine is the third cause of disability in under 50s. J Headache Pain. 2016 Dec;17(1):104. Sieger F a S, Díaz-silva G a, Ardila M, Saavedra-chacón MF. Migraine : a condition unrecognized impact on populations. Acta Neurol Colomb. 2012;28(3):143–51. Schramm SH, Obermann M, Katsarava Z, Diener H-C, Moebus S, Yoon M-S. Epidemiological profiles of patients with chronic migraine and chronic tension-type headache. J Headache Pain. 2013;14(40) Leon-S FE, Pradilla G, Pardo CA et al. The first neuroepidemiological study performed in Colombia, South America, applying the World Health Organization protocol. Neurosciences. 1993;19:127–30. Rueda-Sanchez M, Mantilla-McCormick FJ, Solano MN, Ortiz CJ. Prevalence of headache in an emergency department in Colombia [Spanish] Prevalencia de cefaleas en un servicio de urgencias en Colombia. Rev Neurol. 2005;40(4):209–13. Rueda-Sanchez M, Diaz-Martinez LA. Prevalence and associated factors for episodic and chronic daily headache in the Colombian population. Cephalalgia. 2008;28(3):216–25. Rueda-Sánchez M, Díaz-Martínez LA. Prevalence and associated factors for episodic and chronic daily headache in the Colombian population. Cephalalgia. 2008 Steiner TJ, Birbeck GL, Jensen RH, Katsarava Z, Stovner LJ, Martelletti P. Headache disorders are third cause of disability worldwide. J Headache Pain. 2015;16(1):58 Katsarava Z, Schneeweiss S, Kurth T, Kroener U, Fritsche G, Eikermann A, et al. Incidence and predictors for chronicity of headache in patients with episodic migraine. Neurology. 2004;62:788–90 Riesco N, Garcia-Cabo C, Martinez-Ramos J, Pascual J. How to convince the head of department and managing director of the importance of specialised headache clinics. Rev Neurol. 2015;61 Suppl 1(Supl 1):S13-20. Olesen J. The International Classification of Headache Disorders, 3rd edition. Cephalagia. 2013;33(9):629–808 Silberstein SD, Lipton RB, Dodick DW. Operational diagnostic criteria for chronic migraine: Expert opinion. Headache. 2014;54(7):1258–66 Torres-Ferrus M, Pozo-Rosich P. Posicionamiento de las unidades de cefalea en el ambito de la neurologia: La importancia de la OnabotulinumtoxinA y otras terapias en el tratamiento de la cefalea. Rev Neurol. 2015;61(Supl 1):S3–7 Olesen J, Evers S, Charles A, Hershey A, Lipton R, First M, et al. III Edición de la Clasificación Internacional de las Cefaleas. Int Headache Soc. 2013;23–55 Torelli P, Jensen RH, Tavanaiepour D, Levy RM, Tan X, Dai Y, et al. The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia. 2013;53(9):137–46 Fernández-de-las-Peñas C, Palacios-Ceña D, Salom-Moreno J, López-de-Andres A, Hernández-Barrera V, Jiménez-Trujillo I, et al. Has the prevalence of migraine changed over the last decade (2003-2012)? A Spanish population-based survey. PLoS One. 2014;9(10). Bendtsen L, Fernández-De-La-Peñas C. The role of muscles in tension-type headache. Curr Pain Headache Rep. 2011;15:451–8. Scher AI, Stewart WF, Ricci JA, Lipton RB. Factors associated with the onset and remission of chronic daily headache in a population-based study. Pain. 2003;106:81–9 Schwedt TJ. Chronic migraine. BMJ. 2014;348(G1416):1–11. Bigal ME, Lipton RB, Tepper SJ, Rapoport AM, Sheftell FD. Primary chronic daily headache and its subtypes in adolescents and adults. Neurology. 2004;63(5):843–7 Castillo J, Muñoz P, Guitera V, Pascual J. Epidemiology of chronic daily headache in the general population. Headache. 1999;39(3):190–6 Díaz-Insa S. El mito de la cefalea tensional. Rev Neurol. 2014;58(supl 2):S27-31 Zampieri MAJ, Tognola WA, Galego JCB. Patients with chronic headache tend to have more psychological symptoms than those with sporadic episodes of pain. Arq Neuropsiquiatr. 2014;72(8):598–602 Schwedt TJ, Larson-Prior L, Coalson RS, Nolan T, Mar S, Ances BM, et al. Allodynia and Descending Pain Modulation in Migraine: A Resting State Functional Connectivity Analysis. pain Med. 2014;15:154–65 Baykan B, Ekizoglu E, Karl N, Kocasoy-Orhan E, Zarifoglu M, Saip S, et al. Characterization of Migraineurs Having Allodynia: Results of a Large Population-based Study. Clin J Pain. 2015;32(7):631–5 Aurora SK. Spectrum of illness: understanding biological patterns and relationships in chronic migraine. Neurology. 2009 Feb;72(5 Suppl):S8-13 Aurora SK, Kulthia A, Barrodale PM. Mechanism of chronic migraine. Curr Pain Headache Rep. 2011;15:57–63 Cernuda-Morollon E, Larrosa D, Ramon C, Vega J, Martinez-Camblor P, Pascual J. Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine. Neurology. 2013 Oct;81(14):1191–6 Lindelof K, Ellrich J, Jensen R, Bendtsen L. Central pain processing in chronic tension-type headache. Clin Neurophysiol. 2009;120:1364–70 Cathcart S, Winefield AH, Lushington K, Rolan P. Stress and tension-type headache mechanisms. Cephalalgia. 2010 Oct;30(10):1250–67 Schmidt-Wilcke T, Leinisch E, Straube A, Kämpfe N, Draganski B, Diener HC, et al. Gray matter decrease in patients with chronic tension type headache. Neurology. 2005 Nov;65(9):1483–6 Yancey JR, Koren KG. Chronic Daily Headache: Diagnosis and Management. Am Fam Physician. 2014;89(8):642–8 Bigal ME, Lipton RB. The differential diagnosis of chronic daily headaches: An algorithm-based approach. J Headache Pain. 2007;(8):263–72 Clinch CR. Evaluation of acute headaches in adults. Am Fam Physician. 2001;63(4):685–92. Yu S, Liu R, Yang X, Zhao G, Qiao X, Feng J, et al. Body mass index and migraine: A survey of the Chinese adult population. J Headache Pain. 2012;(13):531–6 Scher AI, Lipton RB, Stewart WF. CME Habitual snoring as a risk factor for chronic daily headache. Neurology. 2003;60:1366–8 Bigal ME, Lipton RB. Modifiable risk factors for migraine progression. Headache. 2006;(46):1334–43 Scher AI, Stewart WF, Lipton RB. Caffeine as a risk factor for chronic daily headache: a population-based study. Neurology. 2004;63(11):2022–7 Bigal ME, Lipton RB. Excessive acute migraine medication use and migraine progression Excessive acute migraine medication use and migraine progression. Neurology. 2008;(71):1821–8 Fernández-De-Las-peñas C, Hernández-Barrera V, Carrasco-Garrido P, Alonso-Blanco C, Palacios-Ceña D, Jiménez-Sánchez S, et al. Population-based study of migraine in Spanish adults: Relation to socio-demographic factors, lifestyle and co-morbidity with other conditions. J Headache Pain. 2010;(11):97–104 Chai NC, Scher AI, Moghekar A, Bond DS, Peterlin BL. Obesity and headache: Part I-A systematic review of the epidemiology of obesity and headache. Headache. 2014;54(2):219–34. Chai NC, Bond DS, Moghekar A, Scher AI, Peterlin BL. Obesity and Headache: Part II – Potential Mechanism and Treatment Considerations. Headache. 2014;54(3):459–71 Silberstein S. The Use of Botulinum Toxin in the Management of Headache Disorders. Semin Neurol. 2016;36(1):092–8 Repositorio EdocUR-U. Rosario Universidad del Rosario instacron:Universidad del Rosario