Brazilian Journal of Medical and Biological Research, Vol 50, Iss 11 (2017) Brazilian Journal of Medical and Biological Research, Volume: 50, Issue: 11, Article number: e6485, Published: 21 SEP 2017 Brazilian Journal of Medical and Biological Research Brazilian Journal of Medical and Biological Research v.50 n.11 2017 Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC