Introduction: Resistance to carbapenems, particularly due to acquired carbapenemases, in Gram-negative bacilli continues to disseminate worldwide. A recent increase in the isolation of carbapenemase producing organisms (CPO) at Canterbury Health Laboratories prompted the need to assess current screening methods. The aim of the study was to evaluate the performance of CHROMagar™ mSuperCARBA™ (MSCA) against the current screening protocol of CHROMagar™ ESBL (CESB) and MacConkey agar with a 10 pg meropenem disc (MAC-Mero), for the recovery of CPO in faecal screening samples. We also compared three chromogenic media, MSCA, CESB and ChromID CARBA SMART (IDCA), against a challenge panel of multi-drug resistant organisms (MDRO), in order to determine the sensitivity and specificity of selection. Methods: 100 screening samples were cultured onto each of MSCA, CESB, and MAC-Mero. Growth of any Gram-negative organism was investigated for the presence of resistance mechanisms. A panel of 50 isolates were inoculated onto each of MSCA, CESB and IDCA. Plates were incubated and examined for growth and typical morphology. Results: For faecal screening, the specificities of CESB, MAC-Mero and MSCA were 73.9%, 96.6% and 88.6% respectively. No CPO were isolated during the study period. For the MDRO challenge, the respective sensitivity and specificity of each media were as follows: CESB 100%, 5.9%, MSCA 97.0%, 88.2%, and IDCA 90.9%, 88.2%. Conclusion: The current screening method consisting of CESB in conjunction with MAC-Mero, was found to have the best overall performance. MSCA showed excellent sensitivity and specificity for the recovery of CPO, and would be considered a beneficial addition in an outbreak situation.