Aim: Compression therapy is the gold standard for venous insufficiency and associated conditions/ulcer management. Patient compliance is essential for success. Reported compliance rates are low, causing patient non healing/patient suffering. Noncompliance has been found to be driven largely by lack of patient comfort with compression wraps. An engineered design, the Dual Compression System, (DCS) contains both short and long stretch bandages. It is designed to increase patient comfort and thus compliance. This study presents compliance data for DCS. Method: 745 total compression wraps were applied to 174 patients with various diagnoses over a 28-day period in busy wound center in the US. Wraps were changed weekly, and patients were followed longitudinally for up to 28 days or until their wounds were closed to calculate degree of compliance over the study period, and reasons for non-compliance were recorded and assessed. The study was done in the winter months. Results / Discussion: Compliance rates of 94.5% were seen. When eliminating those patients whose wraps were removed at another medical appointment, compliance rose to 95.7%. Male compliance was lower than female compliance. No differences were found in compliance via age, diagnosis, or laterality. Conclusion: Comparison of our findings with historically reported data from other compression systems shows a significant improvement in compliance with the DCS. Comfort, absorption, and edema reduction are key factors in patient compliance. Product design impacts the consistent edema reduction leading to improved comfort. DCS manages exudate drainage well by wicking efficiently from the wound, reducing peri-wound maceration. Compliance can ultimately drive patient outcomes which will further lead to health care economic benefits. Repeat study in summer months is indicated.