Background: To describe and understand the experiences and beliefs of caregivers of children with cerebral palsy following botulinum toxin injection. Methods: A descriptive case study approach with focus group interviews was employed. A semi‐structured questionnaire was conducted to collect data. Twenty‐one caregivers of children (3–13 years old) with cerebral palsy were recruited with a maximum variation sampling strategy to gain insight through different perspectives. Qualitative analysis with verbatim transcripts was analysed using a thematic approach. Findings Four themes emerged from qualitative analyses: acceptance of diagnosis, perceptions about treatment, caregivers' experiences with the health environment, and feelings and thoughts after the treatment. Conclusions: This study highlights caregivers' requests for information about the possible long‐term effect of botulinum toxin, as well as information and support to provide the best rehabilitation programme immediately after injection. [ABSTRACT FROM AUTHOR]