Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5 '-Adenosine Monophosphate-Activated Protein Kinase (AMPK)
Resource Type
Journal
Authors
Edmonds, David J. ; Kung, Daniel W. ; Kalgutkar, Amit S. ; Filipski, Kevin J. ; Ebner, David C. ; Cabral, Shawn ; Smith, Aaron C. ; Aspnes, Gary E. ; Bhattacharya, Samit K. ; Borzilleri, Kris A. ; Brown, Janice A. ; Calabrese, Matthew F. ; Caspers, Nicole L. ; Cokorinos, Emily C. ; Conn, Edward L. ; Dowling, Matthew S. ; Eng, Heather ; Feng, Bo ; Fernando, Dilinie P. ; Genung, Nathan E. ; Herr, Michael ; Kurumbail, Ravi G. ; Lavergne, Sophie Y. ; Lee, Esther C. -Y. ; Li, Qifang ; Mathialagan, Sumathy ; Miller, Russell A. ; Panteleev, Jane ; Polivkova, Jana ; Rajamohan, Francis ; Reyes, Allan R. ; Salatto, Christopher T. ; Shavnya, Andre ; Thuma, Benjamin A. ; Tu, Meihua ; Ward, Jessica ; Withka, Jane M. ; Xiao, Jun ; Cameron, Kimberly O.
Source
JOURNAL OF MEDICINAL CHEMISTRY ; MAR 22 2018, 61 6, p2372-p2383, 12p.
Subject
Language
English
ISSN
15204804