Fragment-based discovery of a highly potent, orally bioavailable ERK1/2 inhibitor that modulates the phosphorylation and catalytic activity of ERK1/2
- Resource Type
- Journal
- Authors
- Heightman, Tom D.; Berdini, Valerio; Braithwaite, Hannah; Buck, Ildiko; Cassidy, Megan; Castro, Juan; Courtin, Aurelie; Day, James; East, Charlotte; Fazal, Lynsey; Graham, Brent; Griffiths-Jones, Charlotte; Lyons, John; Martins, Vanessa; Muench, Sandra; Munck, Joanne; Norton, David; O'Reilly, Marc; Palmer, Nick; Pathuri, Puja; Reader, Mike; Rees, David; Rich, Sharna; Richardson, Caroline; Saini, Harpreet; Thompson, Neil; Wallis, Nicola; Walton, Hugh; Wilsher, Nicola; Woolford, Alison; Murray, Chris
- Source
- MOLECULAR CANCER THERAPEUTICS; JAN 2018, 17 1, 2p. Supplement: S
- Subject
- Language
- English
- ISSN
- 15388514