The Oak Ridge National Laboratory (ORNL) staff performed criticality safety calculations documented herein for the fresh fuel region (Region B) of the Northeast Nuclear Energy Company (NNECO) Millstone Unit No. 2 Spent Fuel Pool. The purpose of these calculations was to verify the results reported by NNECO in their application for revision to the Millstone Unit No. 2 technical specifications. All calculations were performed with the SCALE-4.1 code system developed at ORNL. Specifically, the CSAS25 criticality control sequence, which executes the BONAMI, NITAWL-II, and YENO V.a codes, was used to perform all k[sub eff] calculations.