Background: There is evidence for risky consumption of alcohol among medical students.Objectives: The objective of this study is to examine the alcohol consumption of medical students in Dresden.Materials and methods: Between 2011 and 2017, medical students in their second academic semester were recruited to complete the Alcohol Use Disorders Identification Test (AUDIT). Potential influencing factors of drinking patterns as age, gender, psychological distress (BSI-18), class and high school diploma were included in a regression analysis.Results: The cross-sectional results indicated risky scores of the AUDIT (47%), whereas the male students compared with the females showed higher scores (6.73 vs. 4.64; p < 0.001). According to the regression analysis gender (p = 0.000) and psychological distress (p = 0.041; women: p = 0.000) was found to be influencing factors of consumption.Conclusions: The results of this study point out that there is risky alcohol consumption among medical students in their second semester especially among male students. The consumption of alcohol among medical students did not undergo significant changes from 2011–2017. Especially psychological distress mainly among female students seemed to have an influence on consumption.