DNA methylation controls hematopoietic stem cell aging
- Resource Type
- Brief Communication
- Authors
- Krepelova, Anna; Neri, Francesco
- Source
- Nature Aging. 3(11):1320-1322
- Subject
- Language
- English
- ISSN
- 2662-8465
Epigenome deregulation is considered a hallmark of aging; however, the function of the alteration of DNA methylation in aged tissues is a long-standing question. Hong and colleagues reveal the mechanism and consequences of DNA methylation loss at heterochromatin regions in aged hematopoietic stem cells.