Indozyaningrün-Plasmaverschwinderate: Marker einer partiellen Ischämie im Hepatosplanchnikustrakt
- Resource Type
- Original Paper
- Authors
- Thümer, O.; Hüttemann, E.; Sakka, S.G.
- Source
- Der Anaesthesist: Zeitschrift für Anästhesie, Intensivmedizin, Notfall- und Katastrophenmedizin, Schmerzmedizin. April 2007 56(4):339-344
- Subject
- Hepatosplanchnikusdurchblutung
Indozyaningrün-Plasmaverschwinderate
Kritisch kranke Patienten
Hepato-splanchnic blood flow
Indocyanine green plasma disappearance rate
Critically ill patients
- Language
- German
- ISSN
- 0003-2417
1432-055X
Indocyanine green (ICG) is nearly exclusively eliminated from the blood by the liver and the ICG plasma disappearance rate (ICG-PDR) enables assessment of liver blood flow and function. The ICG-PDR which nowadays can be measured non-invasively by a transcutaneous system enables bedside and “on-line” regional monitoring in critically ill patients. So far, only complete lack of ICG-PDR as a sign of non-existing perfusion during liver transplantation has been reported. We describe two patients who developed mesenteric ischemia accompanied by an inadequate increase after revascularisation and an acute drop in the ICG-PDR. In both cases, a computed tomography scan was performed and confirmed an acute abdominal ischemia as indicated by ICG-PDR. Both patients suffered from occlusion of the truncus coeliacus while hepato-splanchnic perfusion via the A. mesenterica superior and the V. portae was maintained. ICG-PDR may be helpful for early detection of hepato-splanchnic ischemia and enables rapid and sufficient initiation of diagnostic and therapeutic procedures. In conclusion, ICG-PDR may be regarded as a clinically attractive bedside monitoring tool for early and reliable detection of partial ischemia in the hepato-splanchnic tract.