Small-Fiber-Neuropathien
- Resource Type
- Continuing Education
- Authors
- Sachau, J.; Enax-Krumova, E.
- Source
- DGNeurologie: Zeitschrift der Deutschen Gesellschaft für Neurologie. 5(6):487-498
- Subject
- Hautbiopsie
Intraepidermale Nervenfaserdichte
Quantitativ Sensorische Testung
Nozizeptiv evozierte Potentiale
Korneale konfokale Mikroskopie
Skin biopsy
Intraepidermal nerve fiber density
Quantitative sensory testing
Nociceptive evoked potentials
Corneal confocal microscopy
- Language
- German
- ISSN
- 2524-3446
2524-3454
Small fiber neuropathy (SFN) is a disease of the peripheral nervous system characterized by isolated or predominant damage to the thinly myelinated Aδ-fibers and/or the unmyelinated C‑fibers. In addition to the clinical symptoms of pain and sensory disturbances that are typically more pronounced distally, the reliable diagnosis of SFN requires evidence of rarefication or dysfunction of the thinly myelinated Aδ-fibers and/or unmyelinated C‑fibers. The present article provides an overview of the diagnostic procedures for detecting SFN, its possible underlying causes, as well as the available treatment options.