172Hf → 172Lu Radionuclide Generator Based on a Reverse-Tandem Separation Scheme
- Resource Type
- Original Paper
- Authors
- Dadakhanov, J. A.; Lebedev, N. A.; Velichkov, A. I.; Karaivanov, D. V.; Baimukhanova, A. E.; Temerbulatova, N. T.; Filosofov, D. V.
- Source
- Radiochemistry. 60(4):415-426
- Subject
- hafnium-172
lutetium-172
radionuclide generator
tantalum target
proton irradiation
perturbed angular correlation method
reverse-tandem separation scheme
distribution coefficients
cation-exchange resin
anion-exchange resin
radiochemical separation
ion-exchange chromatography
- Language
- English
- ISSN
- 1066-3622
1608-3288
The distribution coefficients of Hf(IV) and Lu(III) between Dowex 50W×8 cation exchanger or Dowex 1×8 anion exchanger and mixed HCl–H2C2O4 solutions and between Dowex 50W×8 cation exchanger or Dowex 1×8 anion exchanger and citric acid solutions were determined. A number of modifications of the 172Hf → 172Lu generator, based on reverse separation schemes, were examined. Systems consisting of an anion-exchange resin and a solution of appropriate organic acid were taken as a chemical basis of the generator. Irreversible sorption of 172Lu in generator columns was studied. The optimum operation mode of the 172Hf → 172Lu generator based on the reverse-tandem scheme with periodic transfer of the parent radionuclide into the liquid phase was determined.