Analytical evaluation of thirty-two severe acute respiratory syndrome 2 lateral flow antigen tests demonstrates sensitivity remains with the SARS-CoV-2 Gamma lineage
- Resource Type
- other
- Authors
- Kontogianni, Konstantina; Bengey, Daisy; Wooding, Dominic; Buist, Kate; Greenland-Bews, Caitlin; Williams, Christopher Thomas; Vos, Margaretha de; Santos, Victor Santana; Escadafal, Camille; Adams, Emily Rebecca; Edwards, Thomas; Cubas-Atienzar, Ana Isabel
- Source
- Revista da Sociedade Brasileira de Medicina Tropical. January 2022 55
- Subject
- SARS-CoV-2
SARS-CoV-2 Gamma variant
Variant of concern
Diagnostic tests
- Language
- English
- ISSN
- 0037-8682
Background: The emergence of variants of concern (VOCs) requires an ongoing assessment of the performance of antigen lateral flow tests (Ag-RDTs). The limit of detection (LOD) of 32 Ag-RDTs was evaluated using the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Gamma variant. Methods: Ag-RDTs were performed according to the manufacturer’s instructions with a clinical isolate of the Gamma variant. Results: Twenty-eight of the 32 Ag-RDTs exceeded the World Health Organization criteria. Conclusions: This comprehensive analytical evaluation of Ag-RDTs demonstrated that the test performance was maintained with Gamma VOC.