Recombinant Angiotensin-converting enzyme 2(ACE2) as a potential material for detecting coronavirus (COVID-19)
- Resource Type
- Conference
- Authors
- Siyoung Ha; Oh Seok Kwon
- Source
- 한국진공학회 학술발표회초록집. 2021-02 2021(2):248-248
- Subject
- ACE2
COVID-19
recombinant protein
biosensor
- Language
- Korean
The ACE2 is an appear target for the spike SI protein on Coronavirus specifically SARS-CoV and SARS-CoV-2. The expression of ACE2 in cortical neurons and glials makes them susceptible to SARS-CoV and CoV-2 attack, a possible basis for the occurrence of olfactory syndrome and neurological deficits seen in COVID-19. When the Spike SI protein binds to the enzymatic domain of ACE2 on the cell surface, viruses and enzymes are transfected into the cell. Based on this, the objective of this study was to test the antigenic potential of the recombinant ACE2 protein for subsequent use in diagnostic test.