A New Megastigmane Glucoside from the Aerial Parts of Erythronium japonicum
- Resource Type
- Academic Journal
- Authors
- Seung Young Lee; Il Kyun Lee; Sang Un Choi; Kang Ro Lee
- Source
- Natural Product Sciences. 2012-09 18(3):166-170
- Subject
- Cytotoxicity.
Erythronium japonicum
Liliaceae
Megastigmane
- Language
- Korean
- ISSN
- 1226-3907
2288-9027
The purification of the MeOH extract from the aerial parts of Erythronium japonicum using column chromatography furnished a new megastigmane glucoside, erthrojaponiside (1), together with six known megastigmane derivatives (2 - 7). The structure of the new compound (1) was determined through 1D and 2D NMR spectral data analysis and chemical means. The isolated compounds (1 - 7) were tested for cytotoxicity against four human tumor cells in vitro using a Sulforhodamin B (SRB) bioassay.