This paper considers the evaluation of several factors in Service Engineering from the view of MONOD-ZUKURI. First of all, the definition of the new trend technical term MONODZUKURI is considered in points of view from the several terms and the industrial site of Japan, and its factors are revealed. Next, by investigating the action ac-complishment of human internal, the difficulties of measuring the usability as the factors of Service Engineering is dis-cussed. Then, the admissible measurement method based on the bio-informatics is presented.