PURPOSE: This is a research review. As research results in recent years show, people have different views on oxidative stress. And exercise is one of the important stimulus sources to induce oxidative stress. Therefore, it is necessary to summarize the research results in this field. Oxidative stress is a stress response of cells. Therefore, it is necessary to understand the cellular stress mechanism. CONCLUSION: 1. It is necessary to integrate the concept of cellular stress response. 2. When analyzing a specific signaling pathway or molecular function, it is necessary to first locate the main function of the molecule from the epistatic concept or macroscopic perspective. Secondly, considering the cross characteristics of signal pathway, that is, other functions of the molecule. 3. According to various concepts of cellular stress response, ROS at appropriate concentrations can induce a series of adaptive responses. This is why exercise can boost the body"s ability to function, including oxidative stress. 4. Exercise intensity, amount of exercise and rest period may be the main factors affecting the adverse reactions of exercise-induced oxidative stress. More research is needed to determine exercise programs that cause the least adverse effects.