Few published studies have explored individual differences in susceptibility to inattentional blindness, and those few have focused almost exclusively on cognitive abilities (e.g., working memory capacity). Although both anxiety and depression are associated with attention control deficits, no published studies have examined whether individual differences in emotional distress are associated with inattentional blindness. We conducted 3 studies with college students (n = 134, 196, and 503) to determine whether self-reported levels of negative affect, anhedonic depression, anxious arousal, and worry would predict who would notice an unexpected object. In all 3 samples, none of these measures of emotional distress were directly associated with noticing. However, exploratory analyses revealed suggestive evidence that certain combinations of these factors might predict noticing. We discuss the implications of these findings for understanding the links among attention, awareness, anxiety, and depression.