BACKGROUND:: At present, the foot model was mostly automatic tetrahedral mesh finite element model. Although the automatically partition technology of tetrahedral grid has brought great convenience to the automatically partition of three-dimensional entitative finite element mesh, the mechanical properties are poor. OBJECTIVE:: To construct finite element model of the foot with hexahedral mesh based on CT images. METHODS:: The CT data of normal male foot was selected, using Mimics software to reconstruct the geometric model of the foot, and using NURBS surfaces knot insertion algorithm to refine the geometric model. A high degree of biological simulation finite element model of the human foot was established, using Pam-crash software to undergo collision and simulation analysis. RESULTS AND CONCLUSION:: The results of simulation accorded with results of cadaveric experiments, which showed a good validity of the model. Experiment constructed hexahedral mesh finite element model of the foot based on CT images, foot muscle, tendon and skin were added, thus it could response more realistic to the anatomical structure of the foot, and improved the quality of the finite element model, more effective to study mechanism of the foot injury, so as to provide fundamental data for improve vehicle safety design reference.Li HY, Ding C, Ruan SJ, He LJ.Construction and verification of the foot finite element model. Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu. 2011;15(13): 2381-2384. [http://www.crter.cn http://en.zglckf.com]