EVIDENCE-BASED ANSWER: Weight loss of 4 kg by diet reduces systolic and diastolic blood pressure (BP) by 4.5 and 3.2 mmHg, respectively (strength of recommendation [SOR]: A, systematic review with consistent findings).Weight loss of 1 to 1.2 kg by exercise may produce small reductions in systolic or diastolic BP (SOR: B, mixed quality of studies).Available evidence is inadequate to examine the combined effects of diet and exercise.