BACKGROUND:: Hand-wrist bone maturation as the gold standard for evaluating of bone age has been widely used in the clinical work, but the cervical vertebrae maturation as a new bone age evaluation, with its economic, simple and strong clinical operability has get widespread attention. OBJECTIVE:: To investigate the correlation between adolescentsʼs hand-wrist bone maturation and cervical vertebrae maturation in Urumqi region, and to provide valid reference index for making diagnosis and treatment plan in orthodontics. METHODS:: The lateral cephalograms and hand-wrist radiographs of the 96 cases (34 males, 62 females, 9-15 years of age) were taken before orthodontics treatment. The quality of X-ray image was good, and all the observation indicators were clearly visible without overlapping images. Cervical vertebrae maturation and hand-wrist bone maturation were evaluated. RESULTS AND CONCLUSION:: The correlation coefficient between cervical vertebrae maturation and hand-wrist bone maturation was high (r=0.703, P < 0.01 for males and r=0.728, P < 0.01 for females respectively). The cervical vertebrae maturation and the hand-wrist bone maturation on lateral cephalogram were valid indicators on orthodontic practice to evaluate preciously patients’ state of development and growth. And the cephalogram can avoid additional X-ray radiation that patients received, reduce the economic burden of patients.Yang C, Mi CB, Zu Q, Xu H. Correlation of Han adolescentsʼs hand-wrist bone maturation and cervical vertebrae maturation in Urumqi region.Zhongguo Zuzhi Gongcheng Yanjiu. 2012;16(35): 6641-6645.[http://www.crter.org/crter-2012-qikanquanwen.html](Figure is included in full-text article.)