ABSTRACT: A 56-year-old man underwent a prospective study (ChiCTR2300070081), which is a head-to-head comparison of F-FDG and Ga-DOTATATE PET/MR in EB-positive nonkeratinizing nasopharyngeal carcinoma after chemotherapy. Bilateral cervical abnormal lymph nodes were both detected by F-FDG and Ga-DOTATATE PET/MRI, whereas 2 hepatic lesions only were shown on Ga-DOTATATE, which subsequent pathologically proved to be primary hepatocellular carcinoma.