Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease
- Resource Type
- Academic Journal
- Authors
- Olsson, Eleonor; Winter, Christof; George, Anthony; Chen, Yilun; Howlin, Jillian; Tang, Man-Hung Eric; Dahlgren, Malin; Schulz, Ralph; Grabau, Dorthe; van Westen, Danielle; Fernö, Mårten; Ingvar, Christian; Rose, Carsten; Bendahl, Pär-Ola; Rydén, Lisa; Borg, Åke; Gruvberger-Saal, Sofia K; Jernström, Helena; Saal, Lao H
- Source
- Embo Molecular Medicine. Aug 01, 2015 7(8):1034-1047
- Subject
- Language
- English
- ISSN
- 1757-4676
ABSTRACT: SYNOPSIS: (Figure is included in full-text article.)Serial measurement of circulating tumor DNA (ctDNA) is shown to be a robust and accurate occult metastatic disease biomarker in patients diagnosed with primary breast cancer. Measured ctDNA levels are a quantitative risk factor for poor outcomes. : Serial measurement of circulating tumor DNA (ctDNA) is shown to be a robust and accurate occult metastatic disease biomarker in patients diagnosed with primary breast cancer. Measured ctDNA levels are a quantitative risk factor for poor outcomes.(Figure is included in full-text article.)