INTRODUCTION: Renal transplant recipients are at significantly higher risk for morbidity and mortality compared with the general population, largely attributed to cardiovascular disease (CVD). OBJECTIVE: This study analyzed the incidence of CVE, further categorized as cardiac, cerebrovascular, and peripheral vascular events after kidney transplantation. MATERIALS AND METHODS: This study includes all adult transplanted between October 2010 and December 2016 in the Department of Nephrology of La Rabta Hospital. Traditional cardiovascular risks factors analyzed were age, gender, blood pressure, cholesterol, presence of diabetes, obesity, were time spent on and modality of dialysis before transplantation, type of organ donor (living or deceased) immunosuppressive regimen, acute rejection episodes, and serum creatinine at 3 months post-transplant. RESULTS: In the period of our study, we performed 66 kidney transplantations. During 3 years, CVE was noted in 11 patients (16.6%). The recipients included 8 males and 3 females of overall mean age of 40 years. Initial renal replacement therapy was hemodialysis (HD) in 8 cases. The waiting time on dialysis was superior to 1 year in 81.8%. Pretransplant hypertension was present in 9 cases. Overweight was noted in 36.36%. There are two major and overlapping categories of cardiovascular disease (CVD): * Disorders of cardiovascular perfusion including atherosclerotic CVD (ischemic heart disease (1.5%), cerebrovascular disease (3.07%), and peripheral vascular disease (13.8%) and * disorders of cardiac function including congestive heart failure (1.5%) and left ventricular hypertrophy (21.53%). Among the recipients, one patient has diabetes before transplantation and 5 patients developed new-Onset diabetes. At 3 years Graft survival was 99.96% and patient survival was 99.98%. One patient died because of cerebral vascular event. DISCUSSION: The excessive risk for cardiovascular disease is related to a high prevalence and accumulation of atherogenic risk factors before and after transplantation. Some risk factors associated with cardiac events are irremediable, the most important of them are age and gender. Among the modifiable risk factors, obesity, smoking, hypertension, diabetes, hyperlipidemia, and hyperhomo- cysteinemia are best delineated. The risk for obesity is increased in steroid-treated patients. Removal of dietary restrictions after transplantation and physical inactivity are other important contributors to post transplantation obesity. CONCLUSION: Reduction of cardiovascular morbidity and mortality can improve not only the life expectancy and quality of life of the transplant recipients but also their graft function and survival. Our study has limitations. A larger number of patients and/or a longer time of follow up are probably necessary to establish.