WHATʼS KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Urologists are increasingly involved in the management of patients taking oral anticoagulation (OA) who present with haematuria. It is accepted practice that haematuria in the presence of concurrent anticoagulation requires a full diagnostic evaluation, as it is frequently precipitated by a significant pathological lesion. However, there is limited data on the impact of anticoagulation on the initial inpatient management of these patients. Much of the current evidence is either based around perioperative management of elective patients or, for emergency presentations, is focused on bleeding associated with high morbidity and mortality, such as in the neurosurgical population.In the present study, about half of all admissions with haematuria were for patients on some form of OA. The use of OA strongly predicted for the need for admission for bladder irrigation, regardless of the type of agent or combination of agents used. The use of dual antiplatelet therapy had the strongest association with the need for bladder irrigation, probably due to the well-described synergistic effect between aspirin and clopidogrel. The results of the present study emphasise the importance of early intervention in the management of patients on OA presenting with haematuria. OBJECTIVE: PATIENTS AND METHODS: RESULTS: CONCLUSION