BACKGROUND: Integration of telehealth preparation for nurse practitioner (NP) students varies across programs. PROBLEM: Nurse practitioner students had gaps in the preparation for using telehealth technology to deliver care and manage specific disorders. APPROACH: The purpose of this article is to describe the development and implementation of a telehealth simulation training experience for NP students to prepare them for practice in rural settings. OUTCOMES: Nurse practitioner students from various specialties completed the telehealth simulation training experience. The change in presimulation/postsimulation confidence and readiness scores were statistically significant. CONCLUSION: This telehealth simulation training experience provided an opportunity for NP students to engage in activities to enhance their knowledge and preparation in providing care via telehealth in a rural setting.