Utah State University (USU) and the University of Alabama’s (UA) X-Hab design project created a 3D printed substrate to facilitate plant growth in a microgravity environment. The design team proposed a 3D printed substrate that would allow the plants to have a root support matrix, necessary oxygen flow, and a passive water and nutrient delivery system. This substrate was designed to easily integrate into NASA’s Veggie and Advanced Plant Habitat platforms. 3D printed components are easily replaceable at a relatively low cost. In addition, since research and development has moved to using 3D printers in space, any needed garden components for the blocks could be easily re-printed while in orbit.