Pituitary adenomas within the pituitary stalk, without pituitary gland involvement, are extremely rare. To date, only six cases of pituitary adenomas confined to the pituitary stalk have been reported in English publications; all of which were functional tumors suspected to originate from the pars tuberalis. Herein, we report a case of a non-functioning pituitary adenoma thought to originate from and confined within the pituitary stalk. The patients had normal hormone levels during the initial evaluation and underwent surgery using the endonasal trans-sphenoidal approach. Histopathological examination was performed to confirm the diagnosis. A careful review of the literature was also performed.