Mixed Quadriplegia with Lissencephaly and Dysmyelination
- Resource Type
- Text
- Authors
- Moon, Jeong Lim; Jung, Kyung Heui; Kang, Sae Yoon
- Source
- Journal of Korean Academy of Rehabilitation Medicine. 25(2):330-335
- Subject
- Original Article
- Language
Lissencephaly results from a neuromigrational arrest during first and second trimester of pregnancy and shows hypotonia, marked mental retardation and seizure as predominant features. Myelination is a perinatal process and co-occurence of migrational disorder with myelination disorder is rare. We report a 17-month-old male with mixed quadriplegia and mental retardation with type 1 lissencephaly and dysmyelination of cerebral white matter diagnosed by magnetic resonance imaging.