Gold nanoparticles were synthesized by reacting potassium tetrachloroaurate (KAuCl4), potassium carbonate (K2CO3), and isopropyl alcohol in the presence of fullerene oxide [C60(O)n, n ≥ 1], which was, in turn, prepared from [C60] fullerene and m-chloroperoxybenzoic acid under refluxing conditions. The crystallinity and morphology of the prepared gold nanoparticles were confirmed by UV-vis spectroscopy, X-ray diffraction, and scanning electron microscopy. The activity of the gold nanoparticles in the reduction of 4-nitroaniline was measured in order to determine its capability as a catalyst.