This study aimed to evaluate the effect of post-curing equipment and time on the flexural strength of 3D printing resins produced by a liquid crystal display(LCD) printer. The three 3D printing resins(DENTCA Denture Teeth, DT; C&B 5.0 hybrid, CH; C&B Permanent A2, CP) were divided into four groups according to post-curing time(10 min and 30 min) and equipment with or without vacuum treatment. For the three-point flexural strength test and biaxial strength test were prepared by method according to ISO 10477, ISO 6872, respectively. Flexural strength was measured with universal testing machine. Comparison between post-curing time of each post-curing equipment was analyzed by independent sample t-test and Mann-Whitney U test(α =.05), and comparison between groups according to each 3D printing resin was performed by Kruskal-Wallis test and post-hoc by Bonferroni-Dunn test(α=.05). The flexural strength of the resin post-curing under vacuum was higher than that of the resin post-curing in air. In the comparison according to the post-curing time, in the case of the post-curing equipment without vacuum, the 30 minute curing time showed significantly higher flexural strength than the 10 minute curing time, except for the biaxial flexural strength of CH(P<.05). In the post-curing equipment with vacuum, the three-point flexural strength of all 3D printing resins(DT, CH, and CP) showed a higher value at 30 minute curing time than at 10 minute curing time.