The present study focuses on the performance of metal ferrite catalysts integrated with mesoporous alumina for the high temperature water-gas shift reaction of waste-derived synthesis gas. Ni, Co, and Cu were employed as doped metals for the target reaction in this study. Pure magnetite integrated alumina for HT-WGS was also tested as a reference catalyst. Among the prepared catalysts, copper ferrite integrated with mesoporous alumina showed the highest CO conversion (69%) and 100% selectivity to CO2 at a very high GHSV of 42,000 h-1. The improved performance of the catalyst is correlated with its easier reducibility. In addition, honeycomb-like mesopores Al2O3 also exhibited a beneficial effect on the rapid diffusion of reactants.