Objectives: The purpose of this study is to review the recent clinical study trends on Korean Medicine treatment for Secondary Amenorrhea by analyzing randomized controlled trials. Methods: We searched relevant studies published from electric databases including 4 domestic databases and 3 foreign databases. Data retrieval was conducted on May 30, 2023. and the papers published from January 1, 2018 to May 30, 2023 were included. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 119 studies and 193 studies were searched in each domestic databases and foreign databases, and 9 studies were finally selected. The control group was all treated with only western medicine. Among the treatment group, 2 studies were treated with only oral herbal medicine, 1 study was treated with herbal medicine and acupuncture, 5 studies were treated with combined treatment of herbal medicine and western medicine, 1 study was treated with combined treatment of herbal medicine, acupuncture and western medicine. In all 9 studies, the total effective rate and cure rate were higher in the treatment group than those of the control group (p<0.05). Conclusions: Korean medicine alone or combined with western medicine is more effective for treating Secondary Amenorrhea compared to using western medicine alone.