The aim of the present study was to investigate the effects of three types of mulberry products on the blood glucose and lipid status as well as peroxidative state under diabetic condition. The three types of the products were mulberry liquor prepared by adding 30% ethanol to the crushed fresh fruit, mulbery wine and vinegar by fermentation. Four test materials(M-Liquor, M-Wine, M-Vinegar and M-Powder) for diet experiment were made by freeze-drying the prepared mulberry liquor, wine and vinegar and also by grinding freeze-dried mulberry fruit. Sprague-Dawley male rats weighing 150 ± 10g were randomly assigned to one normal group, and five diabetic groups induced by one intraperitoneal injection of streptozotocin(STZ) at the level of 50 mg/Kg bw. The normal and diabetic control(DM-Control) group were fed diet without the mulberry test materials and M-Liquor, M-Wine and M-Vinegar groups were fed diets containing 1% the test materials each and M-Powder group 5% test material. During three-week of feeding, blood glucose was maintained low in M-Liquor group compared with DM-Control group but low in other three mulberry groups only around two-week period. But serum insulin level was higher both in M-Liquor and M-Vinegar groups and liver glycogen level was higher in all four mulberry groups than DM-Control group. Serum total cholesterol and triglyceride(TG) levels were lower in M-Liquor but HDL-/total cholesterol ratios were higher in M-Powder, M-Liquor and M-Wine groups and liver TG and cholesterol levels tended to be lower in the mullberry groups. Serum levels of thiobarbituric acid reactive substances were not different among the six experimental groups but the liver levels lower in all four mulberry groups. Serum GOT, GPT and BUN levels slightly increased by diabetes but were not changed by the mulberry test materials. These results indicate that mulberry liquor is most effective among mulberry product prepared in the present study for normalizing blood glucose and lipid status and all mulberry products are effective in enhancing antioxidant defense systems in diabetic state without significant liver damage.