Abiotic stress is the major contributor for negatively affecting crop development and productivity in all over world. Rice is sensitive to different abiotic stresses. In this study, I studied some candidate genes that are involved in abiotic stress tolerance in rice. Overexpression of OsSat2, increase salt stress tolerance as well as overall yield in rice. The OsSta2-Ox plants were salt-tolerant at the vegetative stage, based on our calculations of chlorophyll fluorescence (Fv/Fm), fresh and dry weights, chlorophyll concentrations, and survival rates. Under normal paddy field conditions, the Ox plants were somewhat shorter than the WT control but had improved agronomic traits such as higher total grain yield. They were also more tolerant to osmotic stress and hypersensitive to abscisic acid. In addition, Over-expression of dehydrin gene, OsDhn1, improves drought and salt stress tolerance through scavenging of reactive oxygen species in rice as judged by chlorophyll fluorescence (Fv/Fm), fresh and dry weight, water and chlorophyll content, and survival ratio. Furthermore, OsDhn1-OXs showed significantly increased tolerance to methyl viologen (MV)-induced oxidative stress. Under salt and drought stress condition, OsDhn1-OXs maintained relatively low level of H2O2 as compared to wild type plants. Cold stress is very detrimental to crop production. However, only a few genes in rice have been identified with known functions related to cold tolerance. To meet this agronomic challenge more effectively, researchers must take global approaches to select useful candidate genes and find the major regulatory factors. I find out candidate genes in rice that may be involved in cold tolerance by transcriptome analysis between indica and japonica rice variety. I also confirmed that the expression of two randomly chosen genes was increased by cold stress in plants. In addition, overexpression of OsWRKY71 enhanced cold tolerance in ‘Dongjin’, the tested japonica cultivar. Comparisons between japonica and indica rice, based on calculations of plant survival rates and chlorophyll fluorescence, confirmed that the japonica rice was more cold-tolerant. I identify genes involved in abiotic stress tolerance in rice and this can lay down a foundation by which one can develop crop plants with enhanced abiotic stress tolerance. These findings and their utilization will hold promise for rice crop to cope up from certain abiotic stresses.