Sweet potato (Ipomoea batatas L.) is a root that allows healthy eating and combats malnutrition. There is a need for more productive sweet potato genotypes displaying good resistance and a favorable appearance and shape. New genotypes that are more productive, resistant to the main soil pests and with good physical characteristics would contribute to meet the needs of producers and the demands of consumers. The aim of this study was to develop and select sweet potato genotypes regarding agronomic and physical root parameters. The new genotypes were obtained through the cross-linking of 22 parents with commercial characteristics. Subsequently, 386 experimental genotypes were conducted in the feld in an experimental design consisting of augmented blocks with intercalated controls. Aspects related to agronomic, physical root characteristics and resistance to Euscepes postfasciatus were explored. Genotypes with higher performance than the controls were identifed for all assessed parameters. The genotypes UZBD-K-09, UZBD-K-56 and UZBD-K-78, with purple fesh roots, UZBD-F-15 and UZBD-F-34, with orange fesh, and UZBD-K-70, with a white fesh were selected.