Bangladesh, as a newcomer country, is expecting to start her nuclear power journey by 2022. Due toevident reasons, newcomer nuclear countries face several key challenges concerning the development ofnational nuclear safety infrastructure. The paper investigates the status of the 7 key safety infrastructureissues out of the 19 and readiness of the supportive organizations, laboratories, and workforces followingthe International Atomic energy Agency’s status evaluation guide at milestone 3 and foreign countries’practice. Much progress has been achieved at phase 3 regarding the establishments of a few Acts, aregulator, and an operator. However, comprehensive regulatory frameworks, skilled workforces, establishmentsof a few supportive organizations, and laboratories for managing environmental radioactivity,radiological accidents, and radioactive wastes are yet to ready. Several suggestions are made for establishingand expediting radiation monitoring laboratories, a radiological emergency management center, aradioactive waste management company, and technical support organizations for the safety infrastructure. To avoid perceived risks, policymakers and competent authorities need to emphasize creating anoptimized safety infrastructure before commissioning and operating the 1stnuclear power plant safely,securely, and cost-sustainably.