Silver-printed terylene is presented to fabricate anti-electromagnetic radiation Maternity Dress (AMD) withsuperior shielding effectiveness, but the use of noble metal as electromagnetic interference shielding materials enhances costof raw material and restricts its application. In this study, a facile process combined with electroless deposition andhydrophobic treatment to fabricate self-cleaning radiation protection cotton for AMD was established. The active groups onthe plant fiber surface could absorb Sn2+ and Pd2+ through coordination effect, acting as catalytic center, which can catalyzethe reduction of Ni2+ in the plating solution. Ni particle deposited on the its surface with deposited amount of 32 %. Thefabricated material exhibited an shielding effectiveness of 52.5 dB and it meet AMD criteria. Owing to the cooperation of thelow surface energy and rough structure of precipitation, the Ni-plated cotton modified with (3-Mercaptopropyl)trimethoxysilane exhibited remarkable hydrophobicity with water contact angle up to 112.8 o and excellent self-cleaningproperty.