Aspergillus infection is relatively rare disease, and we present a case of orbital aspergillus infection who presented withright orbital pain and swelling. Right orbital lesion was identified on CT, MRI, and PET-CT imaging followed by confirmationof aspergillus on histopathological examination. We demonstrate that Tc-99 m ubiquicidin scan can yield positiveresults in aspergillosis too, enabling its differentiation from non-infective pathologies.