Earth pressure balance (EPB) shield excavation in cohesive strata frequently encounters cutterhead clogging, consuming time and economic costs. Engineering practice shows that cutterhead aperture ratio, soil chamber pressure and soil conditioning have important influences on the clogging behavior of EPB shields. In order to study these factors, a series of laboratory tests were conducted using a setup that can closely simulate the shield tunnelling process. The indicators analyzed were excavation speed, torque, specific energy and soil distribution on the cutterhead. The results indicate that cutterhead aperture and cutter arrangement are important factors in clogging potential. Clogging creates a significant reduction in excavation speed. Torque is not a sensitive parameter reflecting clogging because of the effect of the consolidated soil on the cutters. The presence of soil chamber pressure makes it difficult to remove the clogging through the shearing action of the excavation surface. The injection of a sufficient amount of foam can reduce the risk of shield clogging, but it may lead to an increase of soil adhesion on the cutterhead. The amount of soil that adheres to the cutterhead cannot be used as a classification criterion for clogging potential. Based on experimental phenomena and established studies, a mechanical model called ‘beam-bridge’ was proposed to study the behavior of the soil through the cutterhead opening and damage form of clogging. The results will help to the excavation control of EPB shields.