To solve issues related to hypertrophic scars, such as the risk of bacterial infections, due to the wearing ofcompression garments for extended periods of time, we prepared an antibacterial compression garment fabric (CGF) with agraphene oxide (GO)/chitosan (CS) composite. First, the GO/CS composite was prepared and used as an antibacterial agentfor antibacterial finishing of the CGF. Then, silane coupling agent γ-(methacryloxy) propyl trimethoxysilane (KH570) wasused to modify the GO/CS-finished CGF to improve the washing fastness properties of the antibacterial fabric. Finally, thedurability, physical properties, and biological safety of the antibacterial finished fabrics were studied. We found that the GO/CS composite was successfully synthesized, and the antibacterial finished fabrics were endowed with antibacterial activityagainst both gram-negative bacteria Esherichia coli (E. coli, AATCC 6538) and gram-positive bacteria Staphylococcusaureus (S. aureus, AATCC 25922), with bacteriostatic rates of 92.09 % and 99.33 %, respectively. Moreover, the durability ofthe finished fabric was effectively improved by KH570 treatment. One disadvantage was that the comfort of the antibacterialfinished fabric was affected to a certain extent; however, biological experiments showed that the CGF finished by GO/CS/KH570 showed no potential cytotoxicity on the human body and did not cause skin irritation. The prepared antibacterialfinished CGF based on the GO/CS/KH570 composite could effectively reduce the bacterial infection rates of patients wearingcompression garments, which could significantly alleviate patient suffering.