The removal of toluene using a cycling adsorption and plasma mineralization process was investigated ina packed reactor. The supports of catalysts were optimized in regards to mineralization rate (MR), CO2selectivity (SCO2), and the production of by-products. The hybrid support g-Al2O3-HY showed a muchbetter MR in comparison to that of HY alone. Using hybrid HY-g-Al2O3 as supports, loading Ag–Mn ononly HY or g-Al2O3 had a better MR than loading Ag–Mn on both HY and g-Al2O3. The stability studyshowed that intermediates accumulated on the surface of the catalyst lead to its deterioration.