In order to obtain the high wear- and corrosion-resistant nickel based alloy coatings for laser remanufacturing fretting damaged metal parts which are serviced under high-temperature corrosion and wear conditions, a novel NiCrSiFeBW–CeO2alloy powder was designed by increasing the content of B and Si, adding tungsten and CeO2 using JMatpro software onthe basis of Ni60 alloy powder composition, and the NiCrSiFeBW–CeO2 coating was successfully cladded on 45# steelunder diferent laser energy area densities. The microstructure, wear and corrosion behaviors of the NiCrSiFeBW–CeO2coatings were systematically studied. The results show that novel NiCrSiFeBW–CeO2 coating produced by laser claddingnot only has no cracks but also has both high wear resistance and corrosion resistance due to some ultra-fne compoundparticle phases in situ generated in its structure. Among these phases, the B3Cr5, CrB4, (Cr, Ni)3C2, Cr7C3, W3Cr12Si5 and(Fe, Ni)5Si3 played a signifcant role in reinforcing the wear resistance of the coating, while the B3Cr5, W3Cr12Si5 and CrB4enhanced the corrosion resistance of the coating. The novel NiCrSiFeBW–CeO2 coating prepared under 100 J/mm2EADhas the best comprehensive performance, the wear loss is 7.53×10−5 mm3/N, the Ecorr is − 0.1738 V. Compared with Ni60alloy coating, the novel Ni-based coating not only has a better laser cladded formability but also similar wear resistance andbetter corrosion-resistance. It provides a reference for repairing fretting damaged metal parts by laser cladding the nickelbased coating with high wear and corrosion resistance.