Two-component zeolite-alumina packed dielectric barrier discharge plasma was developed to deeplymineralize toluene. Compared with packing ZSM-5 and g-Al2O3 separately in layers, uniform mixing ofZSM-5 and g-Al2O3 was more conducive to the mineralization of adsorbed toluene in nonthermal plasma. When the mixing ratio of ZSM-5 to g-Al2O3 was 1:2, the mineralization rate reached 80% afterdischarging for 120 min. Ag supported on the catalyst surface significantly improved the selectivity ofCO2. Increased relative humidity had little effect on the mineralization of adsorbed toluene, butsignificantly reduced the byproducts O3 and N2O. The adsorption and plasma mineralizationperformance of Ag/ZSM-5-g-Al2O3 duringfive cycles of toluene adsorption was stable with only thepeak concentration of CO showing a slight upward trend. GC–MS, TG, and XPS characterization of freshand used catalysts revealed deactivation of Ag/ZSM-5-g-Al2O3 in terms of CO oxidation due tointermediate organic residues and decreased amounts of Ag+ and lattice oxygen on the support ZSM-5instead of g-Al2O3.