Acute zonal occult outer retinopathy (AZOOR) is a retinal disease that acutely leads to decreased visual acuity and visual field loss. Abnormal findings of AZOOR cannot be observed with conventional imaging devices. However, some studies have been reported that cone photoreceptor degeneration caused by AZOOR can be observed with an adaptive optics scanning laser ophthalmoscope (AOSLO). In this study, we made a follow-up of AZOOR over a period of eight months using prototype wide field AOSLO developed by TOPCON. A 44 years old female who developed AZOOR in the left eye was followed up using the AOSLO. A low magnitude image (21 degrees field of view) and high magnitude images (1 degree) were captured for same position in the retina each time and cone density was calculated. In result, we observed abnormal findings and its recovery of AZOOR and we found increasing of cone density. In the future, popularization of AOSLO may help understanding of disease progression like AZOOR.