The Epoxidation of Unsaturated Steroids
- Resource Type
- Journal Article
- Authors
- Barry M. BLOOM; Mika HAYANO; Yuichiro KUROSAWA
- Source
- Agricultural and Biological Chemistry. 1961, 25(11):838
- Subject
- Language
- English
- ISSN
- 0002-1369
1881-1280
Data for several additional instances of epoxidation by biological systems at isolated unsaturated sites on steroid structures are presented.These systems include the bovine adrenal, Curvularia lunata and a Curvularia species. This reaction predictably occurred only in the presence of enzymes capable of introducing “axial” hydroxyl functions at saturated carbons of corresponding analogous structures. A discussion of the implication of these findings in terms of the mechanism of the enzymatic hydroxylation reaction is given.