In recent years, diagnostic laparoscopy has widely been used in gastroenterological surgery, gynecology, urology and pediatric surgery. In this present study, we experienced a case of hepatic tumor which was difficult to make preoperative diagnosis due to iodine allergy and the history of surgery but finally diagnosed by laparoscopy. In this case, hand-assisted laparoscopic surgery (hereinafter abbreviated as HALS) was useful for resection. The case was a 30-year-old woman whose tumor was palpated in a left epigastric region in a standing position and a sitting position. In a right lateral position, the tumor exceeded a median line and moved to the right side. No definite diagnosis was made by gastroscopy, abdominal ultrasonography and abdominal CT scan, and the tumor was laparoscopically diagnosed as exophytic one originating from the lateral segment of the liver. The tumor was resected using the HALS by inducing it to the outside of abdominal cavity. The tumor was pathologically diagnosed as focal nodular hyperplasia.