A 67-year-old woman who had been treated for intraductal papillary mucinous carcinoma with bile duct jejunum anastomosis was admitted due to fever. She had undergone three sessions of repeated transcatheter arterial chemoembolizations (TACE) and two sessions of repeated radiofrequency ablation for multiple hepatocellular carcinomas at our hospital. We diagnosed biloma with an abdominal CT scan. We performed endoscopic retrograde cholangiopancreatography (ERCP) and detained an endscopic indwelling biloma drainage tube. The biloma rapidly decreased. ERCP and EBD were useful in this case that had difficulty in the endscopic approach.