A 45-year-old female with a history of hydrocephalus who had been treated with a ventriculoperitoneal shunt (VPS) 20 years ago was admitted with disturbance of consciousness. Cerebral CT indicated dilation of the cerebral ventricle, and external ventricular drainage for decompression was urgently performed by neurosurgeons. Abdominal CT to examine the cause of malfunction of the VPS showed that the peritoneal catheter of the VPS had penetrated and migrated into the ascending colon. Therefore, the patient was referred to our department for surgical removal of the catheter from the colon. Operative findings revealed that the VPS catheter was covered with fibrous tissue and adhered to the ascending colon. The fibrous tissue was detached carefully and the catheter was identified and then removed from the ascending colon after ligation of the catheter close to the penetrating site. The fistula of the ascending colon was sutured. The surgery was completed after confirmation of drainage of cerebral fluid to the abdominal cavity through the catheter. The VPS was totally removed due to meningitis caused by the external ventricular drainage tube.